Bioer Automatic Nucleic Acid Purification Analyzer: Introduction, Principle, Test Requirements, Handling Procedure, Uses, and Keynotes

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Introduction

Bioer Automatic Nucleic Acid Purification Analyzer is an automated system designed to isolate and purify nucleic acid from various samples. It is manufactured by Bioer Technology Co., Ltd, a company based in China. The system utilizes magnetic bead technology and features a compact design with a touch screen interface for easy operation. It can process up to 96 samples simultaneously, making it ideal for high-throughput applications. The Bioer Automatic Nucleic Acid Purification Analyzer is designed to work with a variety of sample types. It includes blood, saliva, and tissue. The purified nucleic acid can be used in downstream applications such as PCR, qPCR, and sequencing.

Bioer Automatic Nucleic Acid Purification Analyzer- Introduction, Principle, Test Requirements, Handling Procedure, Uses, and Keynotes
Fig. Bioer Automatic Nucleic Acid Purification Analyzer Run Shot

Principle

The principle of automatic nucleic acid purification analyzer involves using magnetic beads or silica membranes. It uses to isolate and purify nucleic acids from various biological samples. The analyzer uses a series of steps. It includes sample lysis, binding of nucleic acids to magnetic beads or silica membranes, washing of the beads or membranes to remove impurities, and elution of the purified nucleic acids. The analyzer uses different protocols for different sample types and nucleic acid targets, allowing for high-throughput, automated nucleic acid purification.

Test Requirements

The test requirements for an Automatic Nucleic Acid Purification Analyzer depend on the type of sample being processed. It also depends and the downstream application. Generally, the analyzer requires the following:

  1. Sample input: The sample input could be in the form of blood, serum, plasma, urine, fecal matter, swab, etc.
  2. Reagents and consumables: The analyzer requires specific reagents and consumables depending on the type of nucleic acid purification protocol being used.
  3. Equipment: The analyzer typically requires specific equipment such as centrifuges, pipettes, and tubes.
  4. Power supply: The analyzer requires a reliable power supply to operate efficiently.
  5. User interface: The analyzer should have an intuitive user interface. It allows the user to monitor the purification process and adjust the parameters if necessary.

It is important to carefully follow the manufacturer’s instructions and recommendations for specific test . And also requirements and sample preparation before running a test on an Automatic Nucleic Acid Purification Analyzer.

Handling Procedure

The handling procedure for the Automatic Nucleic Acid Purification Analyzer may vary depending on the specific model and manufacturer. However, in general, the following steps may be involved:

  1. Sample preparation: The sample (e.g., blood, saliva, tissue, etc.) is collected and processed to extract nucleic acid (e.g., DNA, RNA).
  2. Loading of samples: The extracted nucleic acid is loaded into the sample wells of the analyzer’s purification cartridges.
  3. Selection of purification protocol: The appropriate purification protocol is selected based on the type of sample and nucleic acid to be purified.
  4. Initiation of purification: The purification process is initiated and the nucleic acid is purified based on the selected protocol.
  5. Elution of purified nucleic acid: The purified nucleic acid is eluted from the cartridges and collected for downstream applications such as PCR, sequencing, etc.
  6. Cleaning and maintenance: The analyzer is cleaned and maintained according to the manufacturer’s instructions to ensure optimal performance.

It is important to follow the manufacturer’s instructions for proper use and handling of the Automatic Nucleic Acid Purification Analyzer.

Uses

The Bioer Automatic Nucleic Acid Purification Analyzer is used for the extraction and purification of nucleic acids, such as DNA and RNA, from various biological samples. Some of the common applications of this analyzer include:

  1. Clinical diagnostics: The analyzer is used for the isolation and detection of nucleic acids in clinical samples such as blood, serum, plasma, urine, and other body fluids. The purified nucleic acids can be used for disease diagnosis, genetic testing, and monitoring of treatment response.
  2. Microbial detection: The analyzer is used for the extraction and purification of nucleic acids from microbial samples such as bacteria, viruses, and fungi. The purified nucleic acids can be used for microbial detection and identification, antibiotic resistance profiling, and epidemiological studies.
  3. Forensic analysis: The analyzer is used for the extraction and purification of nucleic acids from forensic samples such as bloodstains, saliva, hair, and bone fragments. The purified nucleic acids can be used for DNA profiling and identification.
  4. Environmental monitoring: The analyzer is used for the extraction and purification of nucleic acids from environmental samples such as soil, water, and air. The purified nucleic acids can be used for microbial detection and identification, environmental monitoring, and assessment of microbial diversity.

Keynotes

The Bioer Automatic Nucleic Acid Purification Analyzer is a highly efficient and automated system for the extraction and purification of nucleic acids from various samples. Some keynotes on this analyzer include:

  1. High throughput: The Bioer Automatic Nucleic Acid Purification Analyzer can process a large number of samples in a short time, making it ideal for laboratories that require high throughput.
  2. Automated operation: The system is fully automated, reducing the risk of contamination and human error. The user-friendly interface and intuitive software make it easy to operate.
  3. Versatility: The analyzer can handle various types of samples, including blood, saliva, tissues, and swabs, making it a versatile solution for different laboratory applications.
  4. High purity and yield: The system uses advanced technology to ensure high yield and purity of the extracted nucleic acids, making them suitable for downstream applications such as PCR, sequencing, and genotyping.
  5. Cost-effective: The automated nature of the system reduces the need for manual labor, saving time and costs associated with sample processing.
  6. Compact design: The Bioer Automatic Nucleic Acid Purification Analyzer has a compact design, making it easy to integrate into a laboratory workflow without taking up too much space.
  7. Reliable performance: The system is designed to deliver consistent and reliable results, ensuring reproducibility of experiments and analyses.
  8. Overall, the Bioer Automatic Nucleic Acid Purification Analyzer is a powerful tool for nucleic acid extraction and purification, providing high throughput, automation, versatility, and cost-effectiveness.

Further Readings

  • https://prolabcorp.com/bioer-genepure-NPA-96/
  • https://bioer-china.en.made-in-china.com/product/XSKJRQPjndUW/China-Bioer-Nuclear-Extraction-Automated-Nucleic-Acid-Purification-System.html
  • https://www.bulldog-bio.com/wp-content/uploads/2020/08/GenePure-Pro-manual.pdf
  • https://www.hematologyanalyzerreagent.com/sale-10527497-rna-isolation-kit-auto-extraction-kit-compatible-on-models-allsheng-bioer-zybio-lepu.html
  • https://conference.medgenetics.ru/upload/Bioer%20Technology%20Product%20Intro-711_%D0%A0%D0%9C%D0%A2.pdf

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