Antifungal resistance

Advanced Molecular Fungal Diagnostics: Bridging the Gap in Clinical Mycology

Fungal infections represent a growing global health challenge, causing over 1.7 million deaths annually, with nearly 75% of cases remaining…

1 month ago

Molecular Typing of Fungi: Introduction, Common Molecular Typing Method, and Application

Introduction Molecular typing of fungi uses DNA-based methods to identify species and differentiate strains for clinical, epidemiological, and environmental studies. Fig.…

3 months ago

Sanger Sequencers for Fungal Identification: Introduction, Application, and Keynotes

Introduction Sanger sequencing, developed by Frederick Sanger in 1977, is a chain-termination DNA sequencing method that remains the gold standard for molecular-level fungal…

7 months ago

Blood Culture–Positive Yeasts: Introduction, Common molds, Comparison, and Keynotes

Introduction Unlike molds, yeasts are the most commonly recovered fungi in blood cultures. Candidemia is among the leading causes of…

8 months ago

Blood Culture–Positive Molds: Introduction, Common molds, Comparison, and Keynotes

Introduction Fig. Blood Culture–Positive Mold -Note: The culture bottle shows cottony to fluffy white mycelial growth at the surface. Growth…

8 months ago

Yeasts-Colorimetric Antifungal Susceptibility Testing: Introduction, Principle, Clinical Significance, and Keynotes

Introduction Yeasts, especially Candida and Cryptococcus species, are frequent causes of opportunistic infections in immunocompromised patients. Determining their antifungal susceptibility…

8 months ago

Yeast Identification by Chromogenic Media: Introduction, Principle, Clinical Significance, and Keynotes

Introduction of Yeast Identification by Chromogenic Media (HiMedia) Opportunistic yeasts, especially Candida species, are frequent causes of infections ranging from…

9 months ago

Candida auris PCR-Directly on Clinical Samples: Introduction, Principle, Clinical Significance, and Keynotes

Introduction Candida auris is an emerging multidrug-resistant yeast responsible for outbreaks of healthcare-associated infections worldwide. It is difficult to identify…

9 months ago