Antifungal resistance

Advanced Molecular Fungal Diagnostics: Bridging the Gap in Clinical Mycology

Fungal infections represent a growing global health challenge, causing over 1.7 million deaths annually, with nearly 75% of cases remaining…

3 months ago

Molecular Typing of Fungi: Introduction, Common Molecular Typing Method, and Application

Introduction Molecular typing of fungi uses DNA-based methods to identify species and differentiate strains for clinical, epidemiological, and environmental studies. Fig.…

4 months ago

Sanger Sequencers for Fungal Identification: Introduction, Application, and Keynotes

Introduction Sanger sequencing, developed by Frederick Sanger in 1977, is a chain-termination DNA sequencing method that remains the gold standard for molecular-level fungal…

8 months ago

Blood Culture–Positive Yeasts: Introduction, Common molds, Comparison, and Keynotes

Introduction Unlike molds, yeasts are the most commonly recovered fungi in blood cultures. Candidemia is among the leading causes of…

10 months ago

Blood Culture–Positive Molds: Introduction, Common molds, Comparison, and Keynotes

Introduction Fig. Blood Culture–Positive Mold -Note: The culture bottle shows cottony to fluffy white mycelial growth at the surface. Growth…

10 months ago

Yeasts-Colorimetric Antifungal Susceptibility Testing: Introduction, Principle, Clinical Significance, and Keynotes

Introduction Yeasts, especially Candida and Cryptococcus species, are frequent causes of opportunistic infections in immunocompromised patients. Determining their antifungal susceptibility…

10 months ago

Yeast Identification by Chromogenic Media: Introduction, Principle, Clinical Significance, and Keynotes

Introduction of Yeast Identification by Chromogenic Media (HiMedia) Opportunistic yeasts, especially Candida species, are frequent causes of infections ranging from…

10 months ago

Candida auris PCR-Directly on Clinical Samples: Introduction, Principle, Clinical Significance, and Keynotes

Introduction Candida auris is an emerging multidrug-resistant yeast responsible for outbreaks of healthcare-associated infections worldwide. It is difficult to identify…

10 months ago