Mass spectrometry

Yeast Identification by MALDI-TOF (VITEK): Introduction, Principle, Clinical Significance, and Keynotes

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Yeast Identification by MALDI-TOF (VITEK): Introduction, Principle, Clinical Significance, and Keynotes

Introduction Yeasts, especially Candida species, are among the most important causes of opportunistic fungal infections in humans. Accurate and rapid identification is crucial for guiding antifungal therapy and improving patient outcomes. Traditional phenotypic methods are time-consuming and often misidentify cryptic species. Matrix-Assisted Laser Desorption/Ionization Time-of-Flight …

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Mold Identification by MALDI-TOF (BRUKER)-Introduction, Principle, Clinical Significance, and Keynotes

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Introduction Accurate and timely identification of molds is essential for clinical microbiology, especially in cases of invasive fungal infections caused by Aspergillus, Fusarium, Scedosporium, Mucorales, and other filamentous fungi. Traditional methods based on morphology and phenotypic characteristics are slow, require expertise, and may misidentify cryptic …

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Mold Identification by MALDI-TOF (VITEK): Introduction, Procedure, Benefits, Comparison with other methods, and Keynotes

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Mold Identification by MALDI-TOF (VITEK) Introduction, Procedure, Benefits, Comparison with other methods, and Keynotes

Introduction of Mold identification using MALDI-TOF mass spectrometry Mold identification using MALDI-TOF mass spectrometry, particularly with systems like VITEK MS, offers a rapid and reliable method for identifying fungal species, including molds, in clinical microbiology laboratories.  Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry is a …

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Mycotoxin Detection-Introduction, Detection Methods, and Keynotes

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Mycotoxin Detection-Introduction, Detection Methods, and Keynotes

Introduction Mycotoxin detection involves identifying and quantifying these toxic fungal metabolites in various materials, commonly using chromatographic techniques like HPLC and GC, as well as immunological methods like ELISA and biosensors.  Various detection methods: 1. Chromatographic Techniques: 2. Immunological Techniques: 3. Other Methods: Keynotes Further Readings

Gemella morbillorum-Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

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Gemella morbillorum in Gram staining of culture microscopy

Introduction Gemella morbillorum is a gram-positive bacterium, typically found in the human mouth, throat, and respiratory tract. It occasionally causes infections, particularly in immunocompromised individuals or those with underlying health conditions. Common infections include endocarditis, bacteremia, and abscesses. Notably, it can lead to serious complications …

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Iron Blood Test-Introduction, Test Result, Unit, Reference Range, Test Methods, Clinical Significance, and Keynotes

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Introduction An iron blood test measures how much iron is in your blood. It helps diagnose conditions like anemia or iron overload. This test can show if you’re absorbing iron properly. Doctors often order it when symptoms like fatigue or weakness appear. The test involves …

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MALDI-TOF Mass Spectrometry: Introduction, Principle, Handling Procedure, Application, and Keynotes

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Introduction Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry, commonly abbreviated as MALDI-TOF MS, is a powerful analytical technique used in the field of mass spectrometry. It is widely employed for the identification and characterization of a diverse range of molecules, including proteins, peptides, nucleic acids, carbohydrates, …

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