Colon Cancer: An Overview of Introduction, Types, Pathogenesis,Lab Diagnosis, Treatment, Prevention, and Keynotes

Introduction Colon cancer is a highly prevalent gastrointestinal malignancy originating from the inner lining (mucosal epithelium) of the large intestine. It ranks as the second leading cause of cancer-related deaths worldwide. While historically more common in older individuals, the incidence has steadily risen in younger …

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Melanoma: An Overview of Introduction, Types, Pathogenesis,Lab Diagnosis, Treatment, Prevention, and Keynotes

Introduction Melanoma is the most aggressive and invasive type of skin cancer. It originates from melanocytes, the specialized pigment-producing cells located in the basal layer of the epidermis. While it accounts for less than 5% of all skin cancer cases, it is responsible for over …

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Non-Hodgkin’s Lymphoma: An Overview of Introduction, Types, Pathogenesis,Lab Diagnosis, Treatment, Prevention, and Keynotes

Introduction NHL begins when lymphocytes (B-cells or T-cells) undergo abnormal changes, causing them to multiply uncontrollably and form tumors. These tumors typically start in the lymph nodes but can spread to other organs like the spleen, liver, or bone marrow. Types of NHLThe NHL is …

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Tru-Cut Biopsy (Core Needle Biopsy): Introduction, Procedure, Application, and Keynotes

Introduction A Tru-cut biopsy, also known as a core needle biopsy (CNB), is a minimally invasive diagnostic procedure used to extract a small, solid cylinder (core) of tissue from a suspicious mass. Unlike Fine Needle Aspiration (FNA), which only collects individual cells, a Tru-cut biopsy …

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Breast Cancer: An Overview of Introduction, Types, Pathogenesis,Lab Diagnosis, Treatment, Prevention, and Keynotes

Introduction Breast cancer is the most common malignancy among women worldwide and a leading cause of cancer-related mortality. It arises from the epithelial cells of the breast, most commonly from the ducts or lobules. Although predominantly affecting women, breast cancer can also occur in men. …

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Blood Cancer: An Overview of Introduction, Types, Pathogenesis, Prevention, and Keynotes

Blood Cancer: An Overview of Introduction, Types, Pathogenesis, Prevention, and Keynotes

Introduction Blood cancer, also known as hematological malignancy, refers to a group of cancers that originate in the blood-forming tissues, including the bone marrow, lymphatic system, and blood cells. Unlike solid tumors, blood cancers affect the production, function, and lifespan of blood cells, leading to …

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Fungal Blood Culture-Mold: Introduction, Principle, Clinical Significance, and Keynotes

Fungal Blood Culture Bottle showing fungal growth

Introduction Molds such as Aspergillus, Fusarium, Scedosporium, and members of the Mucorales are important causes of invasive fungal infections, particularly in immunocompromised patients (oncology, transplant, hematology, ICU). Unlike yeasts (Candida, Cryptococcus), which are more frequently recovered from blood cultures, molds are rarely detected in routine …

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Criteria and Decision Framework for Differentiating True Infection from Colonization or Contamination by Aspergillus niger in Cancer Patients

Aspergillus niger growth on SDA

Evaluate the Clinical Context Sample Collection & Repeatability Microscopy & Direct Detection Quantitative Culture & Sterility of Site Serological & Molecular Evidence Radiological Correlation Practical Interpretation Framework Finding Likely Contaminant Possible Colonizer Likely Pathogen Single isolate from 1 sample ✅ ✅ ❌ Repeated isolation from …

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