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Introduction Respiratory tract infections are caused by a wide range of pathogens, including viruses, bacteria, and fungi. Conventional diagnostic methods such as culture, microscopy, and antigen detection are time-consuming and often lack sensitivity. Multiplex polymerase chain reaction (PCR) assays, applied directly to respiratory samples (sputum, …
Introduction of Direct Microscopy Examination of Clinical Samples Direct microscopy examination of clinical samples, or wet mount examination, involves examining clinical specimens under a microscope without prior staining or culturing. This technique provides a rapid assessment of the presence and morphology of microbes, facilitating preliminary diagnosis and …
Introduction The BD BACTEC Blood Culture System is an advanced diagnostic tool for detecting bloodstream infections. It automates microbial culture monitoring with high sensitivity and rapid turnaround time. Additionally, it employs fluorescence-based technology to measure carbon dioxide produced by microbes. Moreover, the system continuously monitors …
Introduction Counterimmunoelectrophoresis is a rapid diagnostic technique in modern immunology laboratories and enhances timely results. Primarily, it separates antigens and antibodies using an electric field for accelerated reactions with precision. Additionally, this method improves immunological assays’ detection speed and remarkably reduces waiting times. Subsequently, it …
Introduction Fungal serology detects antibodies and antigens from fungal pathogens in blood samples. Moreover, it identifies immune responses to various mycoses. Additionally, clinicians use these tests for diagnosing invasive fungal infections. Furthermore, serology supplements culture and microscopic techniques. Consequently, it plays a vital role in …
Introduction Fungal microscopy visualizes fungi in clinical specimens. Moreover, it diagnoses fungal infections rapidly.Additionally, it identifies fungal morphology and structures. Furthermore, it guides antifungal therapy decisions. Consequently, it plays a crucial role in clinical mycology. List of Tests for Fungal Microscopic Examination Firstly, the KOH …
Introduction of India Ink preparation Cryptococcus neoformans is an encapsulated yeast that causes cryptococcal meningitis, particularly in immunocompromised individuals. The capsule is a critical virulence factor, and its visualization is essential for diagnosis. This preparation is a common method used to visualize the capsule. Here, …
Introduction Introduction: Helicobacter pylori (H. pylori) is a bacterium that colonizes the human stomach and is a major cause of various gastrointestinal disorders, including gastritis, peptic ulcers, and even gastric cancer. The discovery of H. pylori‘s role in these diseases revolutionized the field of gastroenterology …