Biochemistry

Anti-Mullerian Hormone (AMH) Test: Introduction, Result, Unit, Normal Range, Test Method, Clinical Significance, and Keynotes

Introduction of Anti-Mullerian Hormone (AMH) Test

An Anti-Mullerian Hormone (AMH) Test measures the level of AMH in the blood which corresponds to egg count in females. It also acts as an indicator of a woman’s reproductive health. Applications of this hormone are as follows-

  1. Estimation of the number of eggs in the ovary
  2. The prognosis (treatment)
  3. To know the response against injectable fertility drugs to stimulate ovaries to mature multiple eggs in preparation for IVF (in vitro fertilization).
  4. To determine if an ovarian mass is a granulosa cell tumor
  5. To diagnose polycystic ovary syndrome (PCOS)

Anti-Mullerian Hormone (AMH) Test- Test Result, Unit, Normal Range, Test Method, and Clinical Significance

Fig. Anti-Mullerian Hormone Test Result, Unit, Normal Range, Test Method, and Clinical Significance

Agewise AMH Level

As AMH level naturally declines with age and its level according to age is given in a table.

Age (years)Blood Level (ng/mL)
253.0
302.5
351.5
401.0
450.5
Table: Level of AMH according to age

Keynotes on Anti-Mullerian Hormone (AMH) Test

  • Anti-Mullerian Hormone (AMH) plays an important role in developing a baby’s sex organs while in the womb. Its level is higher in male babies, as this prevents them from developing female reproductive organs while female babies only need a small amount of AMH for their development.
  • AMH levels naturally decline with age and thus its higher level is not always a good thing. It may be high in some people with polycystic ovary syndrome (PCOS) as shown in the above table.
  • The range of test reports may vary slightly from laboratory to laboratory due to using different equipment.
  • The AMH test can’t predict fertility.
  • Even both men (people assigned male at birth) and women (people assigned female at birth) produce anti-mullerian hormone (AMH), but it is tested only in women especially to provide a woman’s reproductive health status.

Further Readings

  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984648/
  • https://medlineplus.gov/lab-tests/anti-mullerian-hormone-test/
  • https://www.mayocliniclabs.com/test-catalog/Overview/608824
  • https://www.ivf.com.au/planning-for-pregnancy/female-fertility/ovarian-reserve-amh-test
Medical Lab Notes

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