HLA-B27 Test- Introduction, Result-Interpretation, Clinical Significance, and Keynotes
Table of Contents
HLA-B27 stands for Human leukocyte antigen B27. It is a protein found on the surface of our white blood cells (WBCs) and it is a blood test that identifies HLA-B27 proteins. Although most human leukocyte antigens (HLAs) protect your body from harm, HLA-B27 is a specific type of protein that contributes
to immune system dysfunction. An HLA-B27 presence can result in an autoimmune disease or immune-mediated disease, like juvenile rheumatoid arthritis or ankylosing spondylitis.
The result and interpretation of HLA-B27 are as follows-
| Test | Result | Interpretation |
| HLA-B27 | Negative | Absence of HLA-B27 in blood |
| HLA-B27 | Positive | Presence of HLA-B27 in blood |
| Impression: Clinical correlation with the test is mandatory for the treatment. | ||
HLA-B27 test positive is associated with certain autoimmune and immune-mediated diseases like-
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