Mycobacterium tuberculosis MCQs Quiz-A Simple Set of Questionnaire for Examination

Introduction

Below is a set of 15 multiple‐choice questions (MCQs) on Mycobacterium tuberculosis that cover key aspects—from microbiology and diagnosis to treatment and prevention. Each question is followed by four options, with the correct answer indicated afterward. You can use these questions for self‐assessment, classroom quizzes, or exam preparation.

Mycobacterium tuberculosis MCQs Quiz Set

Q1. Which type of organism is responsible for causing tuberculosis?
A. Virus
B. Bacterium
C. Fungus
D. Protozoan

Q2. Who is credited with the discovery of Mycobacterium tuberculosis?
A. Louis Pasteur
B. Robert Koch
C. Edward Jenner
D. Alexander Fleming

Q3. Which of the following culture media is most commonly used for isolating Mycobacterium tuberculosis?
A. MacConkey agar
B. Löwenstein–Jensen medium
C. Blood agar
D. Sabouraud dextrose agar

Q4. Which staining method is the standard for detecting Mycobacterium tuberculosis in clinical specimens?
A. Gram stain
B. Acid-fast stain (Ziehl–Neelsen stain)
C. India ink stain
D. Silver stain

Q5. What is the characteristic pathological feature seen in pulmonary tuberculosis?
A. Non-caseating granulomas
B. Caseating granulomas
C. Suppurative abscesses
D. Interstitial fibrosis

Q6. How is tuberculosis primarily transmitted?
A. Through ingestion of contaminated food
B. Via direct contact
C. By inhalation of airborne droplet nuclei
D. Through sexual contact

Q7. Latent tuberculosis infection (LTBI) is best described as:
A. Active disease with prominent symptoms
B. Infection that is asymptomatic and non-contagious
C. A reinfection following successful treatment
D. TB is limited to extrapulmonary sites only

Q8. A patient with active pulmonary tuberculosis should be managed under which type of infection control precautions?
A. Standard precautions
B. Contact precautions
C. Droplet precautions
D. Airborne precautions

Q9. Which pair of drugs is part of the standard first-line anti-tubercular therapy?
A. Penicillin and Gentamicin
B. Ciprofloxacin and Metronidazole
C. Isoniazid and Rifampicin
D. Vancomycin and Clindamycin

Q10. One of the known side effects of Rifampicin is:
A. Ototoxicity
B. Orange discoloration of body fluids
C. Nephrotoxicity
D. Photosensitivity

Q11. Patients receiving Ethambutol require regular monitoring for which adverse effect?
A. Hearing loss
B. Visual disturbances
C. Hepatotoxicity
D. Renal impairment

Q12. Multi-drug resistant tuberculosis (MDR-TB) is defined as TB that is resistant to at least:
A. Isoniazid and Rifampicin
B. Isoniazid and Ethambutol
C. Rifampicin and Streptomycin
D. Pyrazinamide and Ethambutol

Q13. Which vaccine is used to help prevent tuberculosis, particularly severe forms in children?
A. DTaP
B. MMR
C. BCG (Bacille Calmette–Guérin)
D. Hepatitis B

Q14. What is the typical duration of treatment for a new case of active pulmonary tuberculosis?
A. 1–2 weeks
B. 2–4 months
C. 6–9 months
D. 12–18 months

Q15. Which test is most commonly used to screen for latent tuberculosis infection in high-risk individuals?
A. Chest X-ray
B. Polymerase chain reaction (PCR)
C. Tuberculin skin test (Mantoux test)
D. CT scan

Answer

1. B. Bacterium
2. B. Robert Koch
3. B. Löwenstein–Jensen medium
4. B. Acid-fast stain (Ziehl–Neelsen stain)
5. B. Caseating granulomas
6. C. By inhalation of airborne droplet nuclei
7. B. Infection that is asymptomatic and non-contagious
8. D. Airborne precautions
9. C. Isoniazid and Rifampicin
10. B. Orange discoloration of body fluids
11. B. Visual disturbances
12. A. Isoniazid and Rifampicin
13. C. BCG (Bacille Calmette–Guérin)
14. C. 6–9 months
15. C. Tuberculin skin test (Mantoux test)

Keynote

These MCQs cover a range of topics on Mycobacterium tuberculosis including its microbiology, laboratory diagnosis, clinical presentation, treatment regimens, and preventive measures. They are useful for review and exam preparation in microbiology, infectious diseases, and related healthcare fields.