Nucleic acid extraction of Virus
Table of Contents
The virus has either DNA or RNA nucleic acid and RNA viruses have RNA nucleic acids. During the replication of these viruses, there are at least three types of RNA that must be synthesized. They are- the genome, a copy of the genome (copy genome), and mRNAs. Some of these viruses also synthesize copies of subgenomic mRNAs. RNA-dependent RNA polymerase (RdRp) is the key player in all of these processes. During the viral genome synthesis replicase complex is required while RNA helicases help to unwind base-paired regions of the RNA genome and ATPases supply energy for the polymerization process. Some RNA viruses and causing diseases are mentioned in a table.
| S.No. | Name of viruses | Disease/infection |
| 1. | HIV | AIDS |
| 2. | HCV, HAV, HEV | Hepatitis |
| 3. | Rubella | Rubella (German Measles) |
| 4. | Dengue virus | Dengue fever |
| 5. | Influenza virus | Influenza (flu)/Seasonal influenza |
| 6. | SARS-CoV-2 virus | COVID-19 |
| 7. | Rabies virus( Rabies lyssavirus) | Rabies |
| 8. | Poliovirus | Polio/ poliomyelitis |
| 9. | Noroviruses | Acute gastrointestinal illness |
Viruses family, common names, virion, capsid symmetry, nucleic acid type, and grouping are as follows-
| Virus Family | Common Name | Virion naked/ enveloped | Capsid Symmetry | Nucleic acid type | Group |
| Reoviridae | Reovirus, Rotavirus | Naked | Icosahedral | Ds | III |
| Picornaviridae | Enterovirus Coxsackie, Rhinovirus, Poliovirus, Hepatovirus, Arbovirus | Naked | Icosahedral | Ss | IV |
| Caliciviridae | Norwalk virus, Hepatitis E virus | Naked | Icosahedral | Ss | IV |
| Togaviridae | Rubella virus | Enveloped | Icosahedral | Ss | IV |
| Arenaviridae | Lymphocytic choriomeningitis virus | Enveloped | Complex | Ss(-) | V |
| Flaviviridae | Dengue virus, Hepatitis C virus, Yellow fever virus | Enveloped | Icosahedral | Ss | IV |
| Orthomyxoviridae | Influenzavirus A, Influenzavirus B, Influenzavirus C | Enveloped | Helical | ss(-) | V |
| Paramyxoviridae | Measles virus, Mumps virus, Respiratory syncytial virus, | Enveloped | Helical | ss(-) | V |
| Bunyaviridae | California encephalitis virus, Hantavirus | Enveloped | Helical | ss(-) | V |
| Rhabdoviridae | Rabies virus | Enveloped | Helical | ss(-) | V |
| Filoviridae | Ebola virus, Marburg virus | Enveloped | Helical | ss(-) | V |
| Coronaviridae | Coronavirus | Enveloped | Helical | Ss | IV |
| Astroviridae | Astrovirus | Naked | Icosahedral | Ss | IV |
| Bornaviridae | Borna disease virus | Enveloped | Helical | ss(-) | V |
| Arteriviridae | Arterivirus, Equine Arteritis Virus | Enveloped | Icosahedral | ss | IV |
In the world of modern diagnostics, speed, accuracy, and comprehensiveness are critical—especially when dealing with…
Introduction In today’s rapidly evolving healthcare landscape, the demand for fast, accurate, and accessible diagnostic…
Introduction to MYCOscreen18 PCR Panel Identifying fungal infections quickly and accurately is a critical challenge…
The increasing burden of infectious diseases demands diagnostic solutions that are not only rapid but…
Fungal infections represent a growing global health challenge, causing over 1.7 million deaths annually, with…
Introduction Klebsiella aerogenes (formerly Enterobacter aerogenes) is an opportunistic Gram-negative, facultative anaerobic bacterium responsible for serious healthcare-associated infections…
View Comments
Some truly howling work on behalf of the owner of this web site, dead great subject matter.
A person necessarily help to make critically posts I might state. This is the first time I frequented your web page and up to now? I amazed with the research you made to create this particular publish incredible. Fantastic activity!
I went over this internet site and I believe you have a lot of excellent information, saved to fav (:.
Awsome website! I am loving it!! Will be back later to read some more. I am taking your feeds also
Very interesting points you have noted, thankyou for putting up. "You bluffed me I don't like it when people bluff me. It makes me question my perception of reality." by Andrew Schneider.
I am thankful that I detected this blog, just the right information that I was looking for! .
Incredible! This blog looks just like my old one! It's on a entirely different topic but it has pretty much the same page layout and design. Wonderful choice of colors!
you have a great blog here! would you like to make some invite posts on my blog?
It is truly a nice and useful piece of information. I am glad that you shared this useful information with us. Please keep us up to date like this. Thanks for sharing.
I am no longer certain where you're getting your information, however great topic. I needs to spend some time finding out more or understanding more. Thanks for magnificent information I was in search of this info for my mission.