Biochemistry

Protein Creatinine Ration (PCR) Test of Urine-Test Result, Unit, Normal Range ,Testing Methods, and Keynotes

Introduction of Protein Creatinine Ratio (PCR)

A urine protein creatinine ratio (PCR) test gives information regarding the kidneys working status. It measures the levels of proteins and creatinine in urine. This urine test helps clinicians to diagnose kidney disease and monitor conditions that can damage kidneys. Other names of urine PCR tests are urine protein creatinine ratio (UPCR) test, albumin creatinine Ratio (ACR), and protein to creatinine ratio (P/C ratio).

There is no special preparation for sample collection and thus it is a spot urine sample within the routine clinical practice that is noninvasive, quick, and painless. Proteinuria (high levels of protein in urine) is seen in the conditions like dehydration, infection, pregnancy, heavy physical activity, stress, and kidney diseases.

Protein Creatinine Ratio (PCR) Test of Urine-Test Result, Unit, Normal Range and Testing Methods

Fig. Protein Creatinine Ration (PCR) Test of Urine-Test Result, Unit, Normal Range, and Testing Methods

Keynotes on PCR Test of Urine

  • The normal range of urinary protein is less than 150 milligrams of protein per day.
  • A Protein Creatinine Ration (PCR) Test of Urine is more beneficial than other assays since it measures both creatinine and protein levels in a single urine sample. It is a convenient, reliable alternative to tests needing multiple samples.
  • Urinary creatinine clearance test helps to estimate only creatinine levels while a 24-hour urinary protein test indicates the volume of urine produced over a specific length of time in which urine protein is calculated over a longer period of time, normally 24 hours. But Urine PCR is a combo assay of those above tests.
  • The Protein Creatinine Ration (PCR) Test of urine is a type of kidney function test that detects kidney damage by measuring the amount of protein and creatinine in urine.
  • The urine protein creatinine ratio calculating formula is as follows-(Urine protein(g/L) X 1000)/Urine creatinine(mmol/L)

Further Readings

  • https://www.hopkinsmedicine.org/health/conditions-and-diseases/proteinuria
  • https://www.mayoclinic.org/symptoms/protein-in-urine/basics/causes/sym-20050656
  • https://my.clevelandclinic.org/health/diagnostics/23933-urine-protein-creatinine-ratio
  • https://www.gloshospitals.nhs.uk/our-services/services-we-offer/pathology/tests-and-investigations/albumincreatinine-ratio-acr-and-proteincreatinine-ratio-pcr/
  • https://pubmed.ncbi.nlm.nih.gov/32058809/
  • http://heftpathology.com/item/urine-proteincreatinine-ratio-random-urine.html
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