Biochemistry

Protein Creatinine Ration (PCR) Test of Urine-Test Result, Unit, Normal Range ,Testing Methods, and Keynotes

Introduction of Protein Creatinine Ratio (PCR)

A urine protein creatinine ratio (PCR) test gives information regarding the kidneys working status. It measures the levels of proteins and creatinine in urine. This urine test helps clinicians to diagnose kidney disease and monitor conditions that can damage kidneys. Other names of urine PCR tests are urine protein creatinine ratio (UPCR) test, albumin creatinine Ratio (ACR), and protein to creatinine ratio (P/C ratio).

There is no special preparation for sample collection and thus it is a spot urine sample within the routine clinical practice that is noninvasive, quick, and painless. Proteinuria (high levels of protein in urine) is seen in the conditions like dehydration, infection, pregnancy, heavy physical activity, stress, and kidney diseases.

Protein Creatinine Ratio (PCR) Test of Urine-Test Result, Unit, Normal Range and Testing Methods

Fig. Protein Creatinine Ration (PCR) Test of Urine-Test Result, Unit, Normal Range, and Testing Methods

Keynotes on PCR Test of Urine

  • The normal range of urinary protein is less than 150 milligrams of protein per day.
  • A Protein Creatinine Ration (PCR) Test of Urine is more beneficial than other assays since it measures both creatinine and protein levels in a single urine sample. It is a convenient, reliable alternative to tests needing multiple samples.
  • Urinary creatinine clearance test helps to estimate only creatinine levels while a 24-hour urinary protein test indicates the volume of urine produced over a specific length of time in which urine protein is calculated over a longer period of time, normally 24 hours. But Urine PCR is a combo assay of those above tests.
  • The Protein Creatinine Ration (PCR) Test of urine is a type of kidney function test that detects kidney damage by measuring the amount of protein and creatinine in urine.
  • The urine protein creatinine ratio calculating formula is as follows-(Urine protein(g/L) X 1000)/Urine creatinine(mmol/L)

Further Readings

  • https://www.hopkinsmedicine.org/health/conditions-and-diseases/proteinuria
  • https://www.mayoclinic.org/symptoms/protein-in-urine/basics/causes/sym-20050656
  • https://my.clevelandclinic.org/health/diagnostics/23933-urine-protein-creatinine-ratio
  • https://www.gloshospitals.nhs.uk/our-services/services-we-offer/pathology/tests-and-investigations/albumincreatinine-ratio-acr-and-proteincreatinine-ratio-pcr/
  • https://pubmed.ncbi.nlm.nih.gov/32058809/
  • http://heftpathology.com/item/urine-proteincreatinine-ratio-random-urine.html
Medical Lab Notes

Recent Posts

Klebsiella aerogenes: Introduction, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

Introduction Klebsiella aerogenes (formerly known as Enterobacter aerogenes) is a Gram-negative, rod-shaped, motile bacterium belonging…

2 weeks ago

Staphylococcus pseudintermedius: Introduction, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynote

Introduction and Taxonomy Staphylococcus pseudintermedius is a major veterinary pathogen that serves as a primary…

2 weeks ago

Detecting Low-Yield Target Fungal DNA from Bronchoalveolar Lavage Fluid: Sensitivity Limits of Conventional vs. Quantitative PCR

Introduction 0.5 ng/µL of DNA is detectable and can yield a positive result by PCR.…

1 month ago

Quick Fungal and Bacterial DNA Extraction: Introduction, Principle, Method, Procedure, DNA Concentration, Application, and Keynotes

 Introduction The Quick-DNA™ Fungal/Bacterial Miniprep Kit is designed for the simple and rapid extraction of…

1 month ago

Kocuria rosea -Introduction, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynote

Introduction Kocuria rosea is a Gram-positive, aerobic coccus belonging to the family Micrococcaceae. Formerly classified…

1 month ago

Cladophialophora: Introduction, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynote

Introduction Taxonomy: Belongs to the kingdom Fungi, phylum Ascomycota, and family Herpotrichiellaceae. Synonyms: Cladophialophora bantiana…

2 months ago