Oxidase Test for Bacteria: Introduction, Principle, Procedure, Result Interpretation, and Keynotes
Introduction of Oxidase Test (Kovac’s Method) Gordon and McLeod introduced the application of a dimethyl-phenylenediamine dihydrochloride solution to test for the presence of oxidase systems in 1928. In particular, they used the test to differentiate N. gonorrhoeae (oxidase test positive) from Staphylococcus species and Streptococcus species (oxidase negative). The sensitivity of the …