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Introduction of Bacterial Load (Decoding the CFU) Bacterial load, measured in Colony-Forming Units (CFU), is a fundamental concept in microbiology used to estimate the number of viable (living) microorganisms in a sample. Unlike total cell counts that include dead bacteria, the CFU method only counts …
Introduction Xpert MTB/RIF Ultra is an automated diagnostic test designed for the rapid and simultaneous detection of Mycobacterium tuberculosis (MTB) and resistance to rifampin (RIF). It is a second-generation assay developed by Cepheid to provide significantly higher sensitivity than the original Xpert MTB/RIF, particularly for …
Introduction The Xpert MTB/XDR assay is an advanced molecular diagnostic tool designed by Cepheid to rapidly detect Mycobacterium tuberculosis complex (MTBC) and its resistance to multiple first- and second-line drugs. Launched in 2021, it is categorized as a “low complexity” automated nucleic acid amplification test …
Introduction TrueNat is a rapid, chip-based, and portable molecular diagnostic test. It is developed by Molbio Diagnostics for the detection of tuberculosis (TB) and rifampicin (RIF) resistance. It is the first molecular point-of-care test for TB recommended by the World Health Organization (WHO). Principle The TrueNat system …
Introduction An Interferon-Gamma Release Assay (IGRA) is a modern blood test used to identify if a person is infected with Mycobacterium tuberculosis. It is primarily used to detect latent TB infection (LTBI) and to aid in the diagnosis of active tuberculosis disease. Principle The test is based on the fact …
Introduction The Line Probe Assay (LPA) is a rapid molecular diagnostic test used to detect Mycobacterium tuberculosis complex (MTBC) and its resistance to anti-tuberculosis drugs. It identifies specific mutations in the genes associated with drug resistance by hybridizing amplified DNA onto membrane strips. The LPA is a …
Introduction of COVID-19 Antigen Test SARS-CoV-2 antigen test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is used as a screening test on asymptomatic persons to detect or exclude Coronavirus Disease 2019 (COVID-19) or to determine whether a person who previously was diagnosed with COVID-19 …
Introduction Candida antibody testing measures immunoglobulins (IgG, IgA, and IgM) antibodies in the blood to help detect current or past Candida infections. These antibodies are produced in response to the presence of Candida in the body, assisting the immune system in fighting off the fungus. Principle Purpose …