Aspergillus-Antibody Testing-Introduction, Types of Tests, Clinical Significance, Interpretation of Results, and Keynotes

Aspergillus-Antibody Testing

Introduction Aspergillus antibody testing, specifically IgG and IgE, helps diagnose aspergillosis, particularly chronic pulmonary aspergillosis and allergic bronchopulmonary aspergillosis, by detecting antibodies in the blood against the fungus.  Types of Tests Clinical Significance Interpreting Results Keynotes Further Readings

Coccidioides-Antigen Testing: Introduction, Purpose, How it works, When it’s used, Types of antigen tests, Limitation, and More

Introduction Coccidioides antigen testing, used to diagnose coccidioidomycosis (also known as valley fever),  detects the presence of fungal antigens in bodily fluids like urine, serum, or cerebrospinal fluid. This aids in faster and more accurate diagnosis, especially in immunocompromised individuals or those with severe disease.  …

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Fungal Identification by NGS: Introduction, Principle, Test Methods, Test Procedure, Result-Interpretation, Clinical Significance, and Keynotes

PCR products of fungal DNA from pure culture after amplification with primers

Introduction Fungal identification by NGS (Next-Generation Sequencing) uses advanced DNA sequencing. Moreover, it rapidly detects diverse fungal species. It enhances diagnostic accuracy. Additionally, it supports personalized treatment decisions. Principle NGS sequences fungal DNA directly. Consequently, it generates millions of short DNA reads. Then, bioinformatics tools …

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Paracoccidioides-Antibody Testing: Introduction, Principle, Clinical Significance, and Keynotes

Paracoccidioides-Antibody Testing- Introduction, Principle, Clinical Significance, and Keynotes

Introduction Paracoccidioides antibody testing detects antibodies against the Paracoccidioides species. It plays a vital role in diagnosing paracoccidioidomycosis (PCM). Additionally, clinicians use this test to confirm suspected cases. Moreover, the assay identifies immune responses in patient serum. Furthermore, laboratories perform standardized serological tests such as …

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BD BACTEC Blood Culture System: Introduction, Principle, Processing, and Keynotes

BD BACTEC Blood Culture System_BACTEC 9050 Model-Inner View

Introduction The BD BACTEC Blood Culture System is an advanced diagnostic tool for detecting bloodstream infections. It automates microbial culture monitoring with high sensitivity and rapid turnaround time. Additionally, it employs fluorescence-based technology to measure carbon dioxide produced by microbes. Moreover, the system continuously monitors …

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Counterimmunoelectrophoresis (CIE): Introduction, Application, and Keynotes

The schematic diagram of countermmunoelectrophoresis (CIE)

Introduction Counterimmunoelectrophoresis is a rapid diagnostic technique in modern immunology laboratories and enhances timely results. Primarily, it separates antigens and antibodies using an electric field for accelerated reactions with precision. Additionally, this method improves immunological assays’ detection speed and remarkably reduces waiting times. Subsequently, it …

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Fungal Serology-Introduction, List of Tests, Application, and Keynotes

Fungal Serology-Introduction, List of Tests, Application, and Keynotes

Introduction Fungal serology detects antibodies and antigens from fungal pathogens in blood samples. Moreover, it identifies immune responses to various mycoses. Additionally, clinicians use these tests for diagnosing invasive fungal infections. Furthermore, serology supplements culture and microscopic techniques. Consequently, it plays a vital role in …

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Rifampicin Resistant Indeterminate- Introduction, Result, Cause, Implication, and Summary

Rifampicin Resistant Indeterminate result of Mycobacterium tuberculosis

Introduction “Rifampicin resistant indeterminate” refers to an unclear or inconclusive result in testing for resistance to the antibiotic rifampicin, often used in the treatment of tuberculosis (TB). Here’s a breakdown of the term: Rifampicin Resistant Result and Cause Indeterminate Result: This means the test did …

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