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Introduction Orientia and Rickettsia are two closely related genera of bacteria within the family Rickettsiaceae. Both are small, gram-negative, obligate intracellular pathogens, meaning they can only grow and replicate inside the living cells of their hosts. While they share many clinical features—such as causing fever, …
Introduction A Biosafety Officer (BSO) is a technical expert responsible for the strategic and integrated management of biological risks within an organization. Acting as the human component of a biosafety system, they ensure that laboratory practices, containment, and procedures minimize unintentional exposure to pathogens and …
Introduction Second-line drug susceptibility testing (SL-DST) for tuberculosis is a crucial laboratory procedure designed to detect resistance to anti-TB drugs used when first-line treatment fails (i.e., multidrug-resistant TB – MDR-TB). Principle SL-DST measures the susceptibility of Mycobacterium tuberculosis to specific agents by determining the Critical …
Introduction “Rifampicin resistant indeterminate” refers to an unclear or inconclusive result in testing for resistance to the antibiotic rifampicin, often used in the treatment of tuberculosis (TB). Here’s a breakdown of the term: Rifampicin Resistant Result and Cause Indeterminate Result: This means the test did …
Introduction Salmonella Typhi IgM and IgG tests are diagnostic tools used to detect antibodies in the blood that are specific to the bacterium Salmonella Typhi. It is the causative agent of typhoid fever, a potentially serious and life-threatening illness. These tests play a crucial role …
Introduction The Salmonella Typhi IgM and IgG test is a serological test used to detect antibodies produced by the immune system in response to Salmonella Typhi, the bacterium responsible for causing typhoid fever. This test helps in diagnosing and confirming cases of typhoid fever, a …