D-Zone Test: Introduction, Principle, Procedure, Result-Interpretation, Clinical Significance, and Keynotes

D-Zone Test Positive strain of Staphylococcus aureus

Introduction The D-Zone test identifies inducible clindamycin resistance in bacteria. Typically, it involves using erythromycin and clindamycin discs on an agar plate. When placed near each other, the interaction is observed. If a D-shaped zone appears around clindamycin, resistance is confirmed. Consequently, this test helps …

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Nocardia – Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

Beaded, branching, gram-positive bacilli of Nocardia species

Introduction Nocardia is a genus of aerobic, gram-positive bacteria. It belongs to the actinomycetes group. These bacteria are partially acid-fast due to mycolic acid in their cell walls. They commonly appear as branching filamentous rods. Nocardia species are found in soil and water. They can …

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Rifampicin Resistant Indeterminate- Introduction, Result, Cause, Implication, and Summary

Rifampicin Resistant Indeterminate result of Mycobacterium tuberculosis

Introduction “Rifampicin resistant indeterminate” refers to an unclear or inconclusive result in testing for resistance to the antibiotic rifampicin, often used in the treatment of tuberculosis (TB). Here’s a breakdown of the term: Rifampicin Resistant Result and Cause Indeterminate Result: This means the test did …

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Gemella morbillorum-Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

Gemella morbillorum in Gram staining of culture microscopy

Introduction Gemella morbillorum is a gram-positive bacterium, typically found in the human mouth, throat, and respiratory tract. It occasionally causes infections, particularly in immunocompromised individuals or those with underlying health conditions. Common infections include endocarditis, bacteremia, and abscesses. Notably, it can lead to serious complications …

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K. pneumoniae-Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

K. pneumoniae-Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

Introduction Klebsiella pneumoniae, often abbreviated as K. pneumoniae, is a species of Gram-negative, rod-shaped bacteria commonly found in the human digestive tract, as well as in soil and water. While it is a part of the normal flora in the human gut, K. pneumoniae can …

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E-Test-Introduction, Principle, Test Requirements, Procedure, Result-Interpretation, Application, and Keynotes

Placing Vancomycin E-Test Strip for Staphylococcus aureus

Introduction The E-Test, short for “Epsilometer Test,” is a diagnostic tool used in clinical microbiology and antimicrobial susceptibility testing. It is a method for determining the minimum inhibitory concentration (MIC) of antibiotics or antimicrobial agents against a particular bacterial or fungal pathogen. The E-Test is …

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Serratia liquefaciens: Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

Serratia liquefaciens and Klebsiella pneumoniae growth on CLED agar of Urine Culture

Introduction Serratia liquefaciens is a species of Gram-negative, rod-shaped bacteria belonging to the genus Serratia. This bacterium is known for its diverse distribution in various environmental niches, including water, soil, plants, and human-related habitats. It has also been associated with clinical infections in humans, making …

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Actinomyces-Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

Actinomyces-Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

Introduction Actinomyces is a genus of bacteria that includes various species of filamentous, gram-positive, anaerobic or microaerophilic bacteria. These bacteria are known for their ability to form branching, filamentous structures resembling fungi in infected tissues. Actinomyces species are typically found in the normal flora of …

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