This site is fully related to medical laboratory information for public and health care professionals.
Introduction and Mechanism CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. In nature, bacteria use this system as adaptive immunity against viruses by saving a memory of viral DNA. The engineered laboratory tool consists of two fundamental components: Once Cas9 cuts the DNA, the …
Introduction to the Filters Direct Comparison The critical trade-offs between HEPA and ULPA filtration systems are outlined below: Feature HEPA Filters ULPA Filters Efficiency Rating 99.97%efficiency 99.999%efficiency Target Particle Size 0.3 µm (Most Penetrating Particle Size) 0.12 µm or larger Airflow Resistance Lower static pressure …
Introduction A Laminar Air Flow cabinet creates a sterile work environment by capturing dust and microbes through a filtration system and exhausting the air across the work surface in a uniform, unidirectional stream. It provides product protection but does not protect the operator from hazardous …
Introduction to N95 Particulate Respirators An N95 respirator is a critical tool for personal protective equipment (PPE) in healthcare, industrial, and public safety sectors. Product Comparison: Benehal N95 vs. Magnum MH CUP-S Surgical N95 Choosing between these brands typically depends on whether you require a …
Introduction The Rapid Diagnostic Test (RDT) for Visceral Leishmaniasis (VL), often known as the rK39 test or Kalazar Detect™, is a specific, non-invasive immunochromatographic assay used to detect antibodies against Leishmania parasites in human serum or blood. Visceral Leishmaniasis (Kala-azar) is a severe, potentially fatal …
Introduction HLA-B27 (Human Leukocyte Antigen B27) is a specific genetic variant of the HLA-B gene located on chromosome 6. While HLA proteins normally help the immune system distinguish between the body’s own cells and foreign invaders, the B27 variant is a well-known risk factor for …
Introduction An Interferon-Gamma Release Assay (IGRA) is a modern blood test used to identify if a person is infected with Mycobacterium tuberculosis. It is primarily used to detect latent TB infection (LTBI) and to aid in the diagnosis of active tuberculosis disease. Principle The test is based on the fact …
Introduction The Line Probe Assay (LPA) is a rapid molecular diagnostic test used to detect Mycobacterium tuberculosis complex (MTBC) and its resistance to anti-tuberculosis drugs. It identifies specific mutations in the genes associated with drug resistance by hybridizing amplified DNA onto membrane strips. The LPA is a …