Line Probe Assay (LPA) for Tuberculosis -Introduction, Principle, Test Requirements, Procedure, Result-Interpretation, and Keynotes
Introduction The Line Probe Assay (LPA) is a rapid molecular diagnostic test used to detect Mycobacterium tuberculosis complex (MTBC) and its resistance to anti-tuberculosis drugs. It identifies specific mutations in the genes associated with drug resistance by hybridizing amplified DNA onto membrane strips. The LPA is a …