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Introduction to Advanced Molecular Techniques in Clinical Mycology Clinical mycology laboratories play a crucial role in diagnosing and managing fungal infections. Traditional methods like culture and microscopy are often complemented by advanced molecular techniques to improve the accuracy and speed of fungal identification. Among these …
Introduction of Metallo-beta-lactamases (MBLs) Metallo-beta-lactamases (MBLs) are a group of enzymes produced by certain bacteria that impart resistance to a wide range of beta-lactam antibiotics. These enzymes play a crucial role in the global health challenge posed by antibiotic-resistant bacterial infections. Origin and Mechanism: Clinical …
Introduction of Next-Generation Sequencing (NGS) Platforms Next-Generation Sequencing (NGS) has transformed the field of genomics and our understanding of the intricacies of the genome. Here’s a brief introduction to the topic: What is Next-Generation Sequencing (NGS)? Next-Generation Sequencing (NGS), also known as high-throughput sequencing, is …
Introduction of Restriction fragment length polymorphisms (RFLPs) Restriction Fragment Length Polymorphisms (RFLPs) are a type of genetic variation found within the DNA of organisms, including humans. They were one of the earliest molecular techniques used for genetic analysis and have played a significant role in …
Introduction Multilocus Sequence Typing (MLST) is a molecular typing technique used in microbiology and genetics to classify and differentiate bacterial strains based on their genetic diversity. MLST is particularly valuable for studying the epidemiology and evolution of bacterial pathogens. Here is an introduction to the …
Introduction The BCR-ABL1 genetic test is a diagnostic laboratory test that plays a crucial role in the diagnosis, prognosis, and management of certain types of leukemia, most notably chronic myeloid leukemia (CML) and a subset of acute lymphoblastic leukemia (ALL). This test helps identify the …
Introduction Flow cytometry is a powerful laboratory technique used in the fields of biology, medicine, and immunology to analyze and quantify various physical and chemical characteristics of cells and particles. It allows for the rapid and simultaneous measurement of multiple properties of individual cells as …
Introduction The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Polymerase Chain Reaction (PCR) test is a molecular diagnostic technique used to detect the genetic material of the SARS-CoV-2 virus in individuals suspected of having COVID-19. This test plays a crucial role in identifying active infections …