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Introduction Saprochaete capitata is an emerging opportunistic fungal pathogen that causes severe, frequently fatal systemic infections in profoundly immunocompromised individuals. It is notorious for its intrinsic resistance to echinocandins and high resistance to fluconazole, which often results in breakthrough fungemia during standard empirical antifungal therapy. …
Introduction Leukemia (also spelled leukaemia) is a group of malignant hematological cancers originating in the bone marrow, characterized by the rapid, uncontrolled proliferation of abnormal, non-functional white blood cells (leukocytes). As these malignant cells accumulate, they crowd out healthy red blood cells, functional white blood …
Introduction Molds such as Aspergillus, Fusarium, Scedosporium, and members of the Mucorales are important causes of invasive fungal infections, particularly in immunocompromised patients (oncology, transplant, hematology, ICU). Unlike yeasts (Candida, Cryptococcus), which are more frequently recovered from blood cultures, molds are rarely detected in routine …
Introduction The flow cytometry technique analyzes cells and particles in a fluid suspension. Since it provides rapid and precise results, it is widely used in research and diagnostics. A laser-based system detects fluorescence signals from labeled cells. Because fluorescence markers bind to specific cell components, …
Introduction Counting red blood cells (RBCs) using a Neubauer chamber, also known as a hemocytometer, is a manual technique commonly used in hematology. Here’s a step-by-step guide on how to perform a manual RBC count using a Neubauer chamber: Equipment and Materials Procedure Keynotes on …
Introduction Immunofixation electrophoresis (IFE) is a laboratory technique used primarily in the diagnosis and monitoring of certain blood disorders, particularly those involving abnormal or excessive production of proteins by the immune system. Here’s a brief introduction: This test is a sophisticated tool in the field …
Introduction The transferrin saturation (iron saturation) test is a medical laboratory test used to assess the amount of iron bound to transferrin, a protein that transports iron in the blood. This test provides valuable information about the body’s iron status and is often used in …
Introduction of Lupus Anticoagulant Profile The Lupus Anticoagulant Panel Test, often referred to as the Lupus Anticoagulant Profile or LA Panel, is a series of laboratory tests used to diagnose and monitor lupus anticoagulant (LA) and other antiphospholipid antibodies (aPL). These tests are essential for …