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Medical Lab Notes 
Introduction Aspergillus antibody testing, specifically IgG and IgE, helps diagnose aspergillosis, particularly chronic pulmonary aspergillosis and allergic bronchopulmonary aspergillosis, by detecting antibodies in the blood against the fungus. Types of Tests Clinical Significance Interpreting Results Keynotes Further Readings
Introduction Mycotoxin detection involves identifying and quantifying these toxic fungal metabolites in various materials, commonly using chromatographic techniques like HPLC and GC, as well as immunological methods like ELISA and biosensors. Various detection methods: 1. Chromatographic Techniques: 2. Immunological Techniques: 3. Other Methods: Keynotes Further Readings
Introduction Coccidioides antigen testing, used to diagnose coccidioidomycosis (also known as valley fever), detects the presence of fungal antigens in bodily fluids like urine, serum, or cerebrospinal fluid. This aids in faster and more accurate diagnosis, especially in immunocompromised individuals or those with severe disease. …
Introduction Morphology Prototheca exhibits a unique morphology in cultural media. It forms smooth, creamy colonies on SDA. Moreover, its colonies remain non-filamentous. It produces spherical or oval cells in microscopic preparations. Furthermore, cells display a thick, refractile wall. In addition, internal endospores are occasionally arranged …
Introduction Sclerotic Bodies, also known as Medlar Bodies or muriform cells, are thick-walled, pigmented fungal elements typically observed in chromoblastomycosis. Their diagnostic importance lies in their pathognomonic appearance in tissue sections, which confirms the presence of dematiaceous fungi and helps guide appropriate antifungal treatment. Lab …
Introduction The Aspergillus fumigatus Rapid Azole Screen Test uses a 4-well plate format. It detects azole resistance in fungal isolates. Clinicians request this test to guide effective treatment. Moreover, the assay produces results faster than traditional methods. It minimizes the time needed to decide on …
Introduction Fungal identification by NGS (Next-Generation Sequencing) uses advanced DNA sequencing. Moreover, it rapidly detects diverse fungal species. It enhances diagnostic accuracy. Additionally, it supports personalized treatment decisions. Principle NGS sequences fungal DNA directly. Consequently, it generates millions of short DNA reads. Then, bioinformatics tools …
Introduction This test rapidly detects influenza A and B antigens. It employs a chromatographic assay format. Moreover, it is simple to perform. Principle The test uses immunochromatography. It employs specific antibodies to bind viral antigens. Furthermore, it uses color changes for detection. Thus, it yields …