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Introduction Infection Prevention and Control (IPC) and Healthcare Waste Management (HCWM) are critical systems used to minimize the spread of pathogens, protecting patients, healthcare workers, and the environment. Approximately 15–25% of healthcare waste is considered hazardous, necessitating strict management protocols. IPC is an evidence-based approach …
Introduction to IHC Immunohistochemistry (IHC) is a powerful laboratory technique that combines anatomical, immunological, and biochemical methods to detect specific antigens (proteins) in tissue sections. By exploiting the principle of antibodies binding specifically to antigens in biological tissues, IHC allows for the visualization of protein …
Introduction Hantaviruses are a group of rodent-borne viruses that cause two main life-threatening diseases in humans: Hantavirus Pulmonary Syndrome (HPS) and Hemorrhagic Fever with Renal Syndrome (HFRS). Unlike many other bunyaviruses, they are not transmitted by insects but primarily through the inhalation of aerosolized rodent …
In the world of modern diagnostics, speed, accuracy, and comprehensiveness are critical—especially when dealing with complex infections. The latest advancements in targeted next-generation sequencing (tNGS) are redefining how laboratories detect pathogens and manage antimicrobial resistance (AMR). At the core of this innovation is HyPA (Hyperplex …
The increasing burden of infectious diseases demands diagnostic solutions that are not only rapid but also highly sensitive and comprehensive. Conventional diagnostic methods often fall short due to time delays and limited pathogen coverage. In this context, multiplex real-time PCR technologies are revolutionizing infectious disease …
Introduction Lactococcus garvieae is a Gram-positive, catalase-negative, non-spore-forming coccus, typically arranged in pairs or short chains. It belongs to the lactic acid bacteria group and is well known as a major pathogen in fish (lactococcosis). In humans, it is an emerging opportunistic pathogen, increasingly recognized …
Bronchoalveolar Lavage (BAL) and sputum are commonly used respiratory specimens. Still, they differ significantly in terms of source, quality, diagnostic value, and clinical utility, especially in patients with tuberculosis, fungal infections, pneumonia, and oncology. Basic Definition Feature BAL Sample Sputum Sample Definition Expectorated respiratory secretion …
Introduction KOH Mount of Pleural Fluid is a rapid, direct microscopic test used to detect fungal elements in suspected pleural infections. A 10–20% Potassium Hydroxide (KOH) solution clears cellular debris, fibrin, and protein content in pleural fluid while preserving chitin-rich fungal structures such as hyphae, …