Invasive mold infections

Fungal Blood Culture-Mold: Introduction, Principle, Clinical Significance, and Keynotes

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Fungal Blood Culture Bottle showing fungal growth

Introduction Molds such as Aspergillus, Fusarium, Scedosporium, and members of the Mucorales are important causes of invasive fungal infections, particularly in immunocompromised patients (oncology, transplant, hematology, ICU). Unlike yeasts (Candida, Cryptococcus), which are more frequently recovered from blood cultures, molds are rarely detected in routine …

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Molds-Broth Microdilution Testing (CLSI)-Introduction, Principle, Clinical Significance, and Keynotes

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Introduction Invasive mold infections such as those caused by Aspergillus, Fusarium, Scedosporium, and Mucorales present significant clinical challenges, especially in immunocompromised hosts. Mortality rates are high, and empirical antifungal therapy often fails due to intrinsic or acquired resistance. Standardized antifungal susceptibility testing (AFST) is therefore …

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