Second-Line Drug Susceptibility Testing (SL-DST) for Tuberculosis:Introduction, Principle, Procedure, Result-Interpretation, and Keynotes
Introduction Second-line drug susceptibility testing (SL-DST) for tuberculosis is a crucial laboratory procedure designed to detect resistance to anti-TB drugs used when first-line treatment fails (i.e., multidrug-resistant TB – MDR-TB). Principle SL-DST measures the susceptibility of Mycobacterium tuberculosis to specific agents by determining the Critical …