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Introduction HLA-B27 (Human Leukocyte Antigen B27) is a specific genetic variant of the HLA-B gene located on chromosome 6. While HLA proteins normally help the immune system distinguish between the body’s own cells and foreign invaders, the B27 variant is a well-known risk factor for …
Introduction A Tru-cut biopsy, also known as a core needle biopsy (CNB), is a minimally invasive diagnostic procedure used to extract a small, solid cylinder (core) of tissue from a suspicious mass. Unlike Fine Needle Aspiration (FNA), which only collects individual cells, a Tru-cut biopsy …
Introduction Polymerase Chain Reaction, commonly known as PCR, is a powerful and widely used molecular biology technique that allows for the amplification of specific DNA sequences. Developed by Kary B. Mullis in 1983, PCR revolutionized the field of genetics and has become an essential tool …