Susceptible Dose-Dependent (SDD) Antimicrobial Phenotype- Introduction, Clinical Significance, and Keynotes

Susceptible Dose-Dependent (SDD) Antimicrobial Phenotype- Introduction, Clinical Significance, and Keynotes

Introduction The susceptible dose-dependent (SDD) antimicrobial phenotype is a critical concept in microbiology. It indicates pathogens that require higher doses of antimicrobials for effective treatment. Clinicians must adjust doses to surpass the standard levels. This adjustment ensures the drug’s efficacy against partially resistant pathogens. Moreover, …

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D-Zone Test: Introduction, Principle, Procedure, Result-Interpretation, Clinical Significance, and Keynotes

D-Zone Test Positive strain of Staphylococcus aureus

Introduction The D-Zone test identifies inducible clindamycin resistance in bacteria. Typically, it involves using erythromycin and clindamycin discs on an agar plate. When placed near each other, the interaction is observed. If a D-shaped zone appears around clindamycin, resistance is confirmed. Consequently, this test helps …

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Enterococcus gallinarum – Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

E. gallunarum in Gram stain of culture showing Gram positive cocci in pairs

Introduction Enterococcus gallinarum is a Gram-positive, facultatively anaerobic bacterium. It naturally inhabits the intestines of humans and animals. This bacterium exhibits intrinsic resistance to vancomycin. It can cause infections in immunocompromised patients. It is associated with urinary tract infections and bacteremia. Proper laboratory techniques are …

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Cedecea davisae- Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

Cedecea in wet mount of culture microscopy

Introduction Cedecea davisae is a rare, opportunistic pathogen in the Enterobacteriaceae family. It was first isolated from a human wound. This bacterium can cause infections in immunocompromised individuals. It exhibits resistance to several antibiotics. It is often misidentified due to its rarity. However, proper laboratory …

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Declaration of Helsinki- Introduction, Purpose, Key Points, and Summary

Declaration of Helsinki- Introduction, Purpose, Key Points, and Summary

Introduction of Declaration of Helsinki The Declaration of Helsinki is a set of ethical guidelines and principles for conducting human clinical trials and biomedical research involving human subjects. It was first adopted in 1964 by the World Medical Association (WMA) and has undergone several revisions …

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Carbamazepine Test- Introduction, Test Result, Unit, Normal Range, Test Method, Clinical Significance, and Keynotes

Carbamazepine Test- Introduction, Test Result, Unit, Normal Range, Test Method, Clinical Significance, and Keynotes

Introduction The Carbamazepine Test is a medical diagnostic procedure used to measure the level of carbamazepine in a person’s blood. Carbamazepine is an anticonvulsant medication primarily prescribed to treat epilepsy, certain types of seizures, and bipolar disorder. It works by stabilizing the electrical activity in …

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Prothrombin Time Test and INR (PT/INR): Introduction, Test Result, Normal Range, Test method, Clinical Significance, and Keynotes

Prothrombin Time Test and INR (PT/INR)

Introduction The Prothrombin Time Test (PT) and International Normalized Ratio (INR) are crucial medical tests used to assess the clotting ability of blood. These tests play a vital role in monitoring patients on anticoagulant medications, evaluating bleeding disorders, and assessing liver function. Prothrombin Time Test …

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