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Introduction TrueNat is a rapid, chip-based, and portable molecular diagnostic test. It is developed by Molbio Diagnostics for the detection of tuberculosis (TB) and rifampicin (RIF) resistance. It is the first molecular point-of-care test for TB recommended by the World Health Organization (WHO). Principle The TrueNat system …
Introduction Aspergillus species, particularly Aspergillus fumigatus, are major causes of invasive aspergillosis (IA), especially in immunocompromised patients, such as those with hematological malignancies, transplant recipients, or those with prolonged neutropenia. Diagnosis of IA is often challenging because clinical symptoms and radiological findings are nonspecific. Aspergillus …
Evaluate the Clinical Context Sample Collection & Repeatability Microscopy & Direct Detection Quantitative Culture & Sterility of Site Serological & Molecular Evidence Radiological Correlation Practical Interpretation Framework Finding Likely Contaminant Possible Colonizer Likely Pathogen Single isolate from 1 sample ✅ ✅ ❌ Repeated isolation from …
Introduction The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Polymerase Chain Reaction (PCR) test is a molecular diagnostic technique used to detect the genetic material of the SARS-CoV-2 virus in individuals suspected of having COVID-19. This test plays a crucial role in identifying active infections …
Introduction TB PCR (polymerase chain reaction) for sputum is a laboratory test used in the diagnosis of tuberculosis (TB). It is a molecular diagnostic technique that detects the presence of Mycobacterium tuberculosis (the bacterium that causes TB) DNA in sputum samples. Traditional methods of diagnosing …