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Introduction Broad-range PCR assays for fungi are molecular diagnostic methods designed to detect a wide spectrum of fungal pathogens directly from clinical samples such as blood, BAL, sputum, CSF, tissue biopsies, and sterile body fluids.These assays target highly conserved fungal genomic regions, primarily the Internal …
Introduction Aspergillus species, particularly Aspergillus fumigatus, are major causes of invasive aspergillosis (IA), especially in immunocompromised patients, such as those with hematological malignancies, transplant recipients, or those with prolonged neutropenia. Diagnosis of IA is often challenging because clinical symptoms and radiological findings are nonspecific. Aspergillus …
Introduction Fungemia refers to the presence of fungi in the bloodstream, indicating systemic fungal infection. Candida species are most commonly responsible, but other yeasts and molds may also invade the bloodstream. Fungemia is a medical emergency, especially in ICU patients, immunocompromised hosts, post-surgical cases, and …
Introduction Fungal serology detects antibodies and antigens from fungal pathogens in blood samples. Moreover, it identifies immune responses to various mycoses. Additionally, clinicians use these tests for diagnosing invasive fungal infections. Furthermore, serology supplements culture and microscopic techniques. Consequently, it plays a vital role in …