Sulfonamide Crystals: Introduction, Identification Features, and Clinical Significance
Introduction Sulfonamide crystals are drug-induced urinary crystals that appear in patients receiving sulfonamide (sulfa) therapy, particularly when urine is acidic, concentrated, or dehydrated. They occur due to precipitation of unmetabolized sulfonamide compounds in urine, especially older drugs like sulfadiazine, which are less soluble in acidic …