Purine metabolism

Urate Crystals: Introduction, Identification Features, and Clinical Significance

by
Uriate crystals in urinary sediment microscopic examination at a magnification of 1600X

Introduction Urate crystals, also referred to as uric acid crystals, are metabolic by-products of purine metabolism found in urine. They are frequently observed during urine microscopy, especially in patients with altered pH, dehydration, or metabolic disorders. Their presence can be physiological in concentrated urine or …

Read more

Adenosine Deaminase (ADA)-Introduction, Test Result, Unit, Reference Range, Test Methods, Clinical Significance, and Keynotes

by

Introduction Adenosine Deaminase (ADA) is an enzyme that plays a critical role in purine metabolism, specifically in the conversion of adenosine to inosine. This enzyme is essential for maintaining the balance of nucleotides in cells and is particularly important for the normal functioning of the …

Read more