VITEK 2 Compact and VITEK MS: Introduction, Differences and

Introduction

Table of Contents

The VITEK 2 compact system is an automated microbiology bacteria and yeasts identification and antimicrobial susceptibility system which uses biochemicals for microbial identification whereas, VITEK MS performs the same function by covering a large number of microbes in a short time period at a low cost and works on the principle of matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS).

VITEK 2 Compact System: Introduction, Testing Requirements, Testing Procedure, Result Interpretation and Keynotes — Fig. VITEK 2 Compact System

Differences

The differences between them are as follows-

Features	VITEK 2 Compact	VITEK MS
Working Principle	A fluorogenic methodology for microbial identification and a turbidimetric method for susceptibility testing	MALDI-TOF Mass Spectrometry
Technique	Older	Newer
Time taken for processing	Slower	Faster
Application	For bacteria and yeasts	For bacteria and fungi (yeasts and molds)
Testing cost	Comparatively expensive	Chief
Specificity	Comparatively medium	Comparatively high
Criteria for Acceptance of Identification	Comparatively medium	Comparatively high
Disagreeing results in coagulase-negative staphylococci (CoNS) identification	1. Staphylococcus lugdunensis (93%) 2. Staphylococcus epidermis (99%)	1. Staphylococcus aureus (99.9%) 2. Staphylococcus hominis ssp. hominis (99.9%)

Table: VITEK 2 Compact Versus VITEK MS

Keynotes

The highly mucoid strain of the organism may not provide acceptable results in VITEK 2 Compact and thus alternative methods should be applied for these organisms.
Colonies grown on EMB plates cannot be processed in VITEK 2 Compact because of the carry-over of the dye present in the medium.
Technological advances made by the VITEK MS make it possible to report culture results faster, which has not only the potential to improve patient care, but also shorten the length of stay and reduce health care costs.
API20E/NE,VITEK 2 Compact (VTC), VITEK 2 60 (VT60) and the VITEK MS (VMS) all are product of bioMérieux.
API20E/NE, VITEK 2 Compact (VTC), and VITEK 2 60 (VT60) use biochemical for identification while VITEK MS (VMS) uses MALDI-TOF Mass Spectrometry.
MALDI-TOF mass spectrometry (MS) is widely used technique for the rapid and accurate identification of microbes like bacteria, mycobacteria and certain fungal pathogens in the clinical microbiology laboratory.

Bibliography

https://www.researchgate.net/publication/275582707_Agreement_and_Cost_Comparison_of_VITEK2_Compact_VITEK2_60_VITEK_MS_Systems_and_API20ENE_using_Clinical_Gram-negative_Bacilli_Isolates_from_Jamaica
https://medicallabnotes.com/tag/test-requirements-for-vitek/
https://dohs.gov.np/wp-content/uploads/2021/07/DoHS-Annual-Report-FY-2076-77-for-website.pdf
https://www.gundersenhealth.org/app/files/public/4608fc82-436a-481a-b59f-da2bc1fdb31c/Lab-Policies-Vitek-2-Compact—Identification-and-Susceptibility-Testing-Lab-1512.pdf
https://www.infectiologyjournal.com/articles/benefits-and-limitations-of-malditof-mass-spectrometry-for-the-identification-of-microorganisms.html

Read Also...

20 thoughts on “VITEK 2 Compact and VITEK MS: Introduction, Differences and Keynotes”

My spouse and I absolutely love your blog and find the majority of your post’s to be exactly I’m looking for. Does one offer guest writers to write content for you? I wouldn’t mind publishing a post or elaborating on a few of the subjects you write in relation to here. Again, awesome weblog!

Having read this I thought it was very informative. I appreciate you taking the time and effort to put this article together. I once again find myself spending way to much time both reading and commenting. But so what, it was still worth it!

Hey there, You’ve performed a great job. I will definitely digg it and individually suggest to my friends. I’m confident they will be benefited from this website.

Very interesting topic, regards for putting up.

I intended to compose you this little bit of note to finally thank you so much yet again with your great tips you have discussed on this website. This is strangely generous with you to convey openly all many of us might have offered for sale as an electronic book to generate some dough on their own, even more so now that you could have done it if you desired. These tricks additionally worked to become easy way to be sure that the rest have the identical eagerness much like mine to know many more in respect of this condition. I’m sure there are numerous more pleasurable situations ahead for individuals who read through your site.

great points altogether, you simply gained a new reader. What would you suggest about your post that you made some days ago? Any positive?

Great blog. Much obliged.

I truly appreciate this post. I have been looking everywhere for this! Thank goodness I found it on Bing. You have made my day! Thanks again

Hello, this weekend is good in support of me, because this moment i am reading this impressive educational piece of writing hereat my residence.

I couldn’t refrain from commenting. Very well written!

Wonderful paintings! This is the type of information that are meant to be shared around the internet. Disgrace on Google for now not positioning this submit higher! Come on over and discuss with my site . Thank you =)