Grocott’s Methenamine Silver (GMS) Staining of Mycobacteria:Introduction, Principle, Clinical Significance, Advantage, Disadvantage, and Keynotes
Introduction Grocott’s Methenamine Silver (GMS) stain is a histochemical staining method primarily used to detect fungi in tissue sections. However, it can also stain certain acid-fast organisms like Mycobacteria, especially in tissue biopsies where standard Ziehl-Neelsen or fluorescent stains may miss them. The technique enhances …