Tuberculosis (TB) Laboratory & Quality Assurance Examination

Encircle the correct Answer of the Following question.

1) What is the full form of LQAS?

  • a) Lot Quality Assurance System
  • b) Long Quality Assurance System
  • c) Lab Quality Assurance System
  • d) All of the above

2) What are the components of the Quality Assurance system?

  • a) On-site testing
  • b) Panel testing
  • c) Blinded slide rechecking
  • d) All of the above

3) LQAS is based on…

  • a) Total Negative slide per year
  • b) Slide Positivity Rate
  • c) Both
  • d) None of the above

4) GeneXpert testing detects…

  • a) Only viable TB bacilli
  • b) Only non-viable TB bacilli
  • c) Viable and non-viable TB bacilli
  • d) None

5) The slide positivity rate is determined in LQAS is

  • a) Quarterly
  • b) Half-yearly
  • c) Annually
  • d) Monthly

6) Which value is used for determining the sample size?

  • a) Slide Positivity Rate
  • b) Acceptance Value
  • c) Sensitivity Rate
  • d) All of the above

7) Which value is recommended as sensitivity for determining sample size for a new EQA Program?

  • a) 75%
  • b) 80%
  • c) 85%
  • d) 90%

8) Which result is not good for the TB Microscope centre?

  • a) High false positive
  • b) High false Negative
  • c) All of the above
  • d) None of the above

9) How do you know the number of slides examined by the TB Microscopist in any Quarter?

  • a) From TB Lab Register
  • b) From TB Microscope
  • c) By your estimation
  • d) From the Director level

10) Xpert MTB/RIF assay detects

  • A. Rifampicin resistance
  • B. Rifampicin and Isoniazid
  • C. Isoniazid, Fluoroquinolone, second-line injectables, and ethionamide
  • D. All

11) How do you find the annual sample size for a particular Microscopic centre?

  • a) By the given chart
  • b) By TB Microscopist
  • c) By your own estimation
  • d) None of the above

12) Hierarchy of infection control Measures are

  • A. Administrative Control
  • B. Environmental Control
  • C. Personal Respiratory Protection
  • D. All of the above

13) What is the key goal of the National Strategic Plan for TB in Nepal

  • A. End TB by 2035, prevent TB by 2050
  • B. End TB by 2025, prevent TB by 2035
  • C. End TB by 2030, prevent TB by 2050
  • D. End TB by 2030, prevent TB by 2035

14) Which is the excellent Microscopic center among?

  • a) Result of MC1 Zero False Report with >95% agreement rate
  • b) Result of MC2 Zero False Report with >90% agreement rate
  • c) Result of MCs <5% false Report with >95% agreement rate
  • d) Result of MCs >5% false Report with >95% agreement rate

15) The National Tuberculosis Program (NTP) is adopting “The End TB Strategy.” What is the vision of the End TB Strategy?

  • a) A world Free of TB with zero deaths, disease, and suffering due to TB
  • b) Reduce TB Burden by 2020
  • c) Eliminate TB from Nepal by 2030
  • d) TB-free Nepal by 2050

16) The progress of all TB treatment can be monitored by?

  • a) Follow-up sputum examination
  • b) Active case finding
  • c) By ESR Value
  • d) Mantoux Test

17) What are the methods used for case finding in NTP?

  • a) Active case finding
  • b) Passive case finding
  • c) Both of them
  • d) None of them

18) What are the follow-up months of sputum examination for Treatment monitoring?

  • a) 2 months, 5 months, and the end of treatment
  • b) 3 months, 5 months, and the end of treatment
  • c) 1 month, 3 months, and the end of treatment
  • d) 2 months, 4 months, and the end of treatment

19) How many oil immersion fields need to be examined to declare the smear Negative?

  • a) No Bacilli found in 100 VF
  • b) No Bacilli found in 50 VF
  • c) No Bacilli found in 300 VF
  • d) No Bacilli found in 200 VF

20) Which one is the standard size of smear for AFB?

  • a) 2cm X 2cm
  • b) 1cm X 3 cm
  • c) 1 cm X 2 cm
  • d) 2cm X 4cm
Negative MGIT tube (left) with clear medium versus a positive MGIT tube (right) showing characteristic granular mycobacterial clumping at the bottom
Fig. Negative MGIT tube (left) with clear medium versus a positive MGIT tube (right) showing characteristic granular mycobacterial clumping at the bottom

Answer Sheet

QuestionCorrect Option
1a (Lot Quality Assurance System)
2d (All of the above)
3c (Both)
4c (Viable and non-viable TB bacilli)
5c (Annually)
6a (Slide Positivity Rate)
7b (80%)
8c (All of the above)
9a (From TB Lab Register)
10A (Rifampicin resistance)
11a (By the given chart)
12D (All of the above)
13A (End TB by 2035, prevent TB by 2050)
14a (Result of MC1 Zero False Report with >95% agreement rate)
15a (A world Free of TB with zero deaths, Disease, and suffering due to TB)
16a (2 months, 5 months, and end of treatment)
17c (Both of them)
18a (A world Free of TB with Zero death, Disease, and suffering due to TB)
19a (No Bacilli found in 100 VF)
20c (1 cm X 2 cm)

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