Introduction
Table of Contents
Below is a simple set of 15 multiple‐choice questions (MCQs) on Candida albicans designed as a quiz or examination questionnaire. Each question is provided with four answer choices, and the correct answer is indicated after each question.
Candida albicans MCQs Quiz
1. Which species is the most common cause of candidiasis in humans?
A. Candida glabrata
B. Candida albicans
C. Candida tropicalis
D. Candida parapsilosis
2. Candida albicans is known to exhibit which of the following morphological forms?
A. Yeast only
B. Pseudohyphae and yeast forms
C. Filamentous mold only
D. Bacterial rod
3. Which of the following is NOT a common predisposing factor for Candida infections?
A. Use of broad-spectrum antibiotics
B. Diabetes mellitus
C. Immunosuppression
D. Regular exercise
4. Oral thrush is most frequently associated with an infection by:
A. Aspergillus fumigatus
B. Candida albicans
C. Cryptococcus neoformans
D. Histoplasma capsulatum
5. Vulvovaginal candidiasis is typically characterized by:
A. Profuse watery discharge without itching
B. Thick, white, “cottage cheese-like” discharge with intense itching
C. Yellow-green, malodorous discharge
D. Minimal discharge with severe burning only
6. Which diagnostic test is used to identify the formation of germ tubes in Candida albicans?
A. CHROMagar Candida
B. Germ tube test
C. KOH preparation
D. PCR assay
7. Resistance to azole antifungals in Candida albicans is most commonly associated with:
A. Mutation in the cell wall synthesis pathway
B. Overexpression of efflux pumps
C. Reduced ergosterol production
D. Increased production of melanin
8. The standard laboratory method for diagnosing superficial candidiasis typically involves:
A. Blood culture
B. KOH preparation and culture on Sabouraud dextrose agar
C. Direct fluorescent antibody testing
D. Gram staining
9. For uncomplicated vulvovaginal candidiasis, the first-line treatment is usually:
A. Oral fluconazole
B. Intravenous amphotericin B
C. Oral itraconazole
D. Topical nystatin
10. In cases of systemic (invasive) candidiasis, the reported mortality rate can reach approximately:
A. 5–10%
B. 20–30%
C. 40–60%
D. Over 70%
11. Which statement about Candida albicans is TRUE?
A. It is always pathogenic when isolated.
B. It is a normal component of human microbiota that can become opportunistic.
C. It cannot form biofilms on medical devices.
D. It is inherently resistant to all classes of antifungal agents.
12. Biofilm formation by Candida albicans is especially problematic on which of the following?
A. Skin surfaces
B. Mucosal surfaces
C. Indwelling medical devices (e.g., catheters)
D. Blood vessels
13. The morphological switch from yeast to hyphal form in Candida albicans is associated with:
A. Reduced pathogenicity
B. Enhanced adhesion and tissue invasion
C. Decreased biofilm formation
D. Loss of metabolic activity
14. Which enzyme is considered a key virulence factor contributing to tissue invasion in Candida albicans?
A. Lipase
B. Secreted aspartyl proteinase (SAP)
C. Catalase
D. Urease
15. Which of the following laboratory methods is used for antifungal susceptibility testing of Candida isolates?
A. Kirby-Bauer disk diffusion
B. Broth microdilution assay
C. ELISA
D. Gram staining
Answer
- B. Candida albicans
- B. Pseudohyphae and yeast forms
- D. Regular exercise
- B. Candida albicans
- B. Thick, white, “cottage cheese-like” discharge with intense itching
- B. Germ tube test
- B. Overexpression of efflux pumps
- B. KOH preparation and culture on Sabouraud dextrose agar
- A. Oral fluconazole
- C. 40–60%
- B. It is a normal component of human microbiota that can become opportunistic.
- C. Indwelling medical devices (e.g., catheters)
- B. Enhanced adhesion and tissue invasion
- B. Secreted aspartyl proteinase (SAP)
- B. Broth microdilution assay
Keynote
This quiz covers key areas—including epidemiology, morphology, pathogenesis, diagnosis, and treatment—providing a broad overview suitable for examination purposes on Candida albicans.