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In the world of modern diagnostics, speed, accuracy, and comprehensiveness are critical—especially when dealing with complex infections. The latest advancements in targeted next-generation sequencing (tNGS) are redefining how laboratories detect pathogens and manage antimicrobial resistance (AMR). At the core of this innovation is HyPA (Hyperplex …
Introduction of MDR Candida NGS MDR Candida NGS refers to the use of Next-Generation Sequencing for the detection, identification, and resistance gene profiling of multidrug-resistant (MDR) Candida species, such as Candida auris, Candida glabrata, and others resistant to azoles, echinocandins, or polyenes. Next-generation sequencing (NGS) …
Introduction Next-generation sequencing (NGS) in Clinical Mycology is revolutionizing the diagnosis, typing, and antifungal resistance profiling of fungal pathogens. Application Here’s an overview of its applications: Candida spp.: Aspergillus spp.: CYP51A: Azole resistance due to mutations in ergosterol synthesis. Advantages of NGS in Clinical Mycology …