This site is fully related to medical laboratory information for public and health care professionals.
Fungal infections represent a growing global health challenge, causing over 1.7 million deaths annually, with nearly 75% of cases remaining undiagnosed or diagnosed too late. The increasing burden of antifungal resistance (AMR) further complicates treatment outcomes, highlighting an urgent need for rapid, accurate, and comprehensive …
Introduction Sterility testing in a GMP-compliant mycology laboratory is a critical quality assurance process used to confirm that pharmaceutical products, culture media, reagents, water systems, and laboratory environments are free from viable microorganisms, including fungi and yeasts.It follows regulatory guidelines defined by WHO, EU-GMP, USP …
Introduction of Yeast Identification by Chromogenic Media (HiMedia) Opportunistic yeasts, especially Candida species, are frequent causes of infections ranging from superficial candidiasis to life-threatening systemic disease. Conventional identification based on culture and biochemical tests can be time-consuming and may not reliably distinguish closely related species. …
Introduction The Auxacolor System is a commercially available biochemical-based yeast identification method widely used in clinical microbiology laboratories. It provides a simple, standardized approach to identifying medically important yeasts, including Candida, Cryptococcus, Trichosporon, and others. Unlike molecular tools or MALDI-TOF MS, Auxacolor is inexpensive, does …
Introduction of MDR Candida NGS MDR Candida NGS refers to the use of Next-Generation Sequencing for the detection, identification, and resistance gene profiling of multidrug-resistant (MDR) Candida species, such as Candida auris, Candida glabrata, and others resistant to azoles, echinocandins, or polyenes. Next-generation sequencing (NGS) …
Introduction Mycosel Agar is a selective culture medium to isolate pathogenic fungi from samples containing a mix of fungi and bacteria. It’s designed to suppress the growth of non-pathogenic fungi and bacteria, allowing for the isolation and identification of pathogenic fungi. Principle Cycloheximide inhibits the growth …
Introduction The Aspergillus fumigatus Rapid Azole Screen Test uses a 4-well plate format. It detects azole resistance in fungal isolates. Clinicians request this test to guide effective treatment. Moreover, the assay produces results faster than traditional methods. It minimizes the time needed to decide on …
Introduction Fungal identification by NGS (Next-Generation Sequencing) uses advanced DNA sequencing. Moreover, it rapidly detects diverse fungal species. It enhances diagnostic accuracy. Additionally, it supports personalized treatment decisions. Principle NGS sequences fungal DNA directly. Consequently, it generates millions of short DNA reads. Then, bioinformatics tools …