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Introduction The NALC-NaOH (N-acetyl-L-cysteine–sodium hydroxide) method is the gold standard for processing clinical specimens in mycobacteriology laboratories. It prepares contaminated samples (like sputum) for successful culture on liquid media (such as the BD BACTEC™ MGIT™ 960) and solid media. Clinical samples from non-sterile sites naturally …
Introduction The BD BACTEC™ MGIT™ 960 (Mycobacteria Growth Indicator Tube) is a fully automated, high-volume culture system designed for the rapid detection of mycobacteria and subsequent drug susceptibility testing (DST). Developed by Becton Dickinson (BD), this nonradiometric system addresses the critical clinical need for accelerated …
Introduction Mycobacteriology specimen packaging and shipping involve the standardized containment and transport of biological materials suspected of containing Mycobacterium species. Because organisms such as Mycobacterium tuberculosis are highly infectious airborne pathogens (Risk Group 3), their transport is strictly governed by the U.S. Department of Transportation (DOT) and …