Leucine Crystals: Introduction, Identification Features, and Clinical Significance

Leucine crystal in urine microscopy at a magnification of 1600X

Introduction Leucine crystals are rare urinary findings that typically appear in patients with severe liver disease, such as advanced cirrhosis, severe hepatitis, or metabolic disorders like maple syrup urine disease. They form in acidic urine and indicate a disturbance in amino acid metabolism. Identification Features …

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Urate Crystals: Introduction, Identification Features, and Clinical Significance

Uriate crystals in urinary sediment microscopic examination at a magnification of 1600X

Introduction Urate crystals, also referred to as uric acid crystals, are metabolic by-products of purine metabolism found in urine. They are frequently observed during urine microscopy, especially in patients with altered pH, dehydration, or metabolic disorders. Their presence can be physiological in concentrated urine or …

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Ascitic Fluid Microscopy: Introduction, Principle, Test Requirements, Procedure, Finding, Clinical Significance, and Keynotes

Collected Ascitic Fluid

Introduction Ascitic fluid microscopy is a laboratory diagnostic method used to examine peritoneal (ascitic) fluid obtained via paracentesis. It helps in identifying cells, microorganisms, and crystals that provide clues about underlying causes such as infection, malignancy, liver disease, or systemic disorders. Principle The principle of …

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Pleural Fluid Microscopy: Introduction, Principle, Test Requirements, Procedure, Finding, Clinical Significance, and Keynotes

Collected Pleural Fluid-

Introduction Pleural fluid is the liquid collected from the pleural space between the lung and chest wall. Microscopic examination of pleural fluid plays a key role in identifying the underlying cause of pleural effusion. It helps distinguish between transudates and exudates, detect infectious organisms, malignant …

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Fat Droplet-Introduction, Clinical Significance, Lab Diagnosis, and Keynotes

Fat droplet found in urinary sediment microscopic examination

Introduction Clinical Significance of Fat Droplet Laboratory Diagnosis 1. Specimen: 2. Microscopy: 3. Special Stains: Keynotes on Fat Droplet Further Readings

Coccidioides-Antibody Testing: Introduction, Clinical Significance, Test methods, Result-Interpretation, and Additional Information

Coccidioides-Antibody Testing: Introduction, Clinical Significance, Test methods, Result-Interpretation, and Additional Information

Introduction For diagnosing coccidioidomycosis (Valley Fever), AI-assisted Coccidioides antibody testing uses enzyme immunoassays (EIA) and immunodiffusion (ID) or complement fixation (CF) tests to detect antibodies against the fungus Coccidioides immitis.  Clinical Significance Types of Tests Used:  How the Tests Work:  Result-Interpretation AI in Coccidioides Antibody Testing …

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Fever Panel Test-Introduction, Test Result, Unit, Normal Range, Test Method, Clinical Significance, and Keynotes

Fever Panel Test-Introduction, Test Result, Unit, Normal Range, Test Method, Clinical Significance, and Keynotes

Introduction The Fever Panel Test is a comprehensive diagnostic technique designed to identify the root cause of fever. Moreover, it combines multiple tests into a single panel for efficient detection of ecological agents/pathogens. Furthermore, this assay evaluates bacterial, viral, and parasitic infections contributing to fever …

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Direct Bilirubin Test-Introduction, Test Result, Unit, Reference Range, Test Methods, Clinical Significance, and Keynotes

Direct Bilirubin Test-Introduction, Test Result, Unit, Reference Range, Test Methods, Clinical Significance, and Keynotes

Introduction The Direct Bilirubin Test measures the levels of conjugated bilirubin in the blood, assessing liver and bile duct health. Moreover, direct bilirubin is water-soluble, making it easier for the body to excrete through bile. In addition, this test helps detect liver diseases, such as …

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