MALDI-TOF Mass Spectrometry: Introduction, Principle, Handling Procedure, Application, and Keynotes

Introduction Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry, commonly abbreviated as MALDI-TOF MS, is a powerful analytical technique used in the field of mass spectrometry. It is widely employed for the identification and characterization of a diverse range of molecules, including proteins, peptides, nucleic acids, carbohydrates, …

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Pleural Fluid Culture and Sensitivity: Introduction, Report, Clinical Significance, Common Pathogens, and Keynotes

Pleural fluid for laboratory diagnosis

Introduction Pleural fluid culture and sensitivity is a diagnostic test used to identify and determine the antibiotic susceptibility of microorganisms present in the pleural fluid. The pleural fluid is a clear fluid that accumulates between the two layers of the pleura, the membrane that surrounds …

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Herpes Simplex Virus (HSV): Introduction, Morphology, Pathogenicity, Lab Diagnosis, Treatment, Prevention, and Keynotes

Tzanck Smear- Positive of Herpes Simplex Virus (HSV)

Introduction Herpes Simplex Virus (HSV) is a common and highly contagious virus that infects humans. It belongs to the family Herpesviridae and is characterized by its ability to establish a lifelong infection in the host. HSV exists in two main types: HSV-1 and HSV-2. Transmission: …

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Polymerase Chain Reaction (PCR): Introduction, Principle, Types, Application, and Keynotes

Amplicons or DNA or RNA fragments of amplification or replication events

Introduction Polymerase Chain Reaction, commonly known as PCR, is a powerful and widely used molecular biology technique that allows for the amplification of specific DNA sequences. Developed by Kary B. Mullis in 1983, PCR revolutionized the field of genetics and has become an essential tool …

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Cerebrospinal fluid (CSF) Culture and Sensitivity: Introduction, Report, Clinical Significance, Common Pathogens, and Keynotes

Aspirated Cerebrospinal fluid (CSF) for Culture -Sensitivity, and more

Introduction Cerebrospinal fluid (CSF) culture and sensitivity is a medical laboratory test performed to detect and identify any infectious organisms that may be present in the cerebrospinal fluid. The CSF is a clear and colorless fluid that surrounds the brain and spinal cord, providing essential …

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Varicella-Zoster Antibody, IgG Assay:Introduction, Test Result, Unit, Normal Range, Test Method, Clinical Significance, and Keynotes

Varicella-Zoster Antibody, IgG Assay:Introduction, Test Result, Unit, Normal Range, Test Method, Clinical Significance, and Keynotes

Introduction Varicella-zoster antibody, IgG assay, is a medical test used to measure the levels of varicella-zoster virus (VZV) specific immunoglobulin G (IgG) antibodies in the blood. VZV is the virus responsible for causing chickenpox (varicella) and can also re-emerge later in life as shingles (herpes …

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Compound Microscope: Introduction, Principle, Parts, Uses, Care and Maintenance, and Keynotes

Compound Microscope- Introduction, Principle, Parts, Uses, Care and Maintenance, and Keynotes_

Introduction The compound microscope is a fundamental and widely used optical instrument that allows us to magnify and observe small objects or specimens that are otherwise invisible to the naked eye. It is an essential tool in various scientific fields, including biology, medicine, microbiology, and …

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Simple Microscope: Introduction, Principle, Parts, Uses, Care and Maintenance, and Keynotes

Introduction A simple microscope is a basic optical instrument used for magnifying small objects or specimens that are not visible to the naked eye. It consists of a single lens that can be either convex or concave, mounted in a frame with a handle or …

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