This site is fully related to medical laboratory information for public and health care professionals.
Introduction of Klebsiella ozaenae Klebsiella pneumoniae subspecies ozaenae (Klebsiella ozaenae) is a Gram-negative bacterium (GNB), primarily associated with atrophic rhinitis (ozena), a chronic condition of the nasal cavity characterized by tissue thinning and unpleasant odor. It is also known as a normal inhabitant of the oral and …
Introduction Candida antibody testing measures immunoglobulins (IgG, IgA, and IgM) antibodies in the blood to help detect current or past Candida infections. These antibodies are produced in response to the presence of Candida in the body, assisting the immune system in fighting off the fungus. Principle Purpose …
Introduction To effectively evaluate mushrooms’ antifungal activity against clinical dermatophytes, laboratories require specialized equipment and techniques for fungal isolation, identification, and susceptibility testing. These include media for fungal culture, microscopy for morphological identification, and standardized methods like agar-based disk diffusion (ABDD) or broth microdilution for antifungal …
Introduction of Biosafety Cabinet (BSC) A biosafety cabinet (BSC) is a specialized enclosed, ventilated laboratory workspace that is designed for safely handling materials contaminated with pathogens or toxins. It protects the operator, the product being worked on, and the environment. BSC uses high-efficiency particulate air (HEPA) filters to …
Introduction of Direct Microscopy Examination of Clinical Samples Direct microscopy examination of clinical samples, or wet mount examination, involves examining clinical specimens under a microscope without prior staining or culturing. This technique provides a rapid assessment of the presence and morphology of microbes, facilitating preliminary diagnosis and …
Introduction Aspergillus conidia are produced on unbranched conidiophores with a vesicle, while Penicillium conidia are produced on branched conidiophores, forming brush-like structures. Both have small conidia, but differ in color and germination patterns. The LPCB mount shows the hallmark features of an Aspergillus conidiophore: This brush‑ or radiate‑head …
Introduction of Cryptococcal Antigen (CrAg) Testing Cryptococcal antigen (CrAg) testing detects the presence of antigens produced by the Cryptococcus fungus in body fluids, aiding in the diagnosis of cryptococcosis, particularly meningitis. This test helps identify infection early, even before visible symptoms appear, and is crucial for timely …
Introduction of Mold identification using MALDI-TOF mass spectrometry Mold identification using MALDI-TOF mass spectrometry, particularly with systems like VITEK MS, offers a rapid and reliable method for identifying fungal species, including molds, in clinical microbiology laboratories. Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry is a …