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Introduction Histoplasma capsulatum is a dimorphic fungus responsible for histoplasmosis, a systemic mycosis prevalent in endemic regions such as the Ohio and Mississippi River valleys, parts of Latin America, Africa, and Asia. Rapid and reliable diagnosis is crucial since clinical features may mimic tuberculosis, malignancy, …
Introduction Candida antibody testing measures immunoglobulins (IgG, IgA, and IgM) antibodies in the blood to help detect current or past Candida infections. These antibodies are produced in response to the presence of Candida in the body, assisting the immune system in fighting off the fungus. Principle Purpose …
Introduction For diagnosing coccidioidomycosis (Valley Fever), AI-assisted Coccidioides antibody testing uses enzyme immunoassays (EIA) and immunodiffusion (ID) or complement fixation (CF) tests to detect antibodies against the fungus Coccidioides immitis. Clinical Significance Types of Tests Used: How the Tests Work: Result-Interpretation AI in Coccidioides Antibody Testing …
Introduction Fungal identification plays a vital role in diagnosing infections. Mycologists use various methods to identify fungal species. Firstly, conventional techniques rely on morphology and culture characteristics. Additionally, molecular assays enhance detection accuracy. Researchers now employ advanced tools to expedite fungal identification. Moreover, timely identification …
Introduction to Advanced Molecular Techniques in Clinical Mycology Clinical mycology laboratories play a crucial role in diagnosing and managing fungal infections. Traditional methods like culture and microscopy are often complemented by advanced molecular techniques to improve the accuracy and speed of fungal identification. Among these …
Introduction Candidiasis is an infection caused by Candida fungi, commonly Candida albicans. These fungi naturally live on the skin and inside the body, like in the mouth, throat, gut, and vagina, without causing problems. However, if the environment inside the body changes or the immune …
Introduction Multilocus Sequence Typing (MLST) is a molecular typing technique used in microbiology and genetics to classify and differentiate bacterial strains based on their genetic diversity. MLST is particularly valuable for studying the epidemiology and evolution of bacterial pathogens. Here is an introduction to the …
Introduction Pulsed-field gel electrophoresis (PFGE) is a powerful laboratory technique used in molecular biology and genetics to separate and analyze large DNA molecules, such as genomic DNA, by their size. PFGE is particularly valuable when studying organisms with complex genomes, such as bacteria, yeast, and …